Trulicity (Dulaglutide)

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Product Details


Trulicity is a prescription Type 2 diabetes treatment medication that is used to lower blood sugar levels and commonly prescribed for Type 2 diabetics at risk of cardiovascular events. Dulaglutide is a GLP-1 agonist drug that works by mimicking body hormones that effectively regulate blood glucose levels but are lacking in people who are Type 2 diabetic. Trulicity stimulates insulin secretion and lowers glucagon secretion when blood glucose levels are elevated. This medication may be taken with Metformin depending on what your doctor determines to be your best approach to Type 2 diabetes management and controlling blood sugar.

Fact Table
Formula C2646H4044N704O836S18
License US DailyMed, EU EMA
Bioavailability 47-60%
Legal status Rx-Only
Chemical Name Dulaglutide
Elimination half-life 5 days
Dosage (Strength) 0.75mg/0.5ml (pens), 1.5mg/0.5ml (pens)
Pregnancy Consult a doctor
Brands Trulicity
Protein binding Unknown
PubChem CID Not Assigned
MedlinePlus a614047
ChEBI Not Assigned
ATC code A10BJ05
DrugBank DB09045
KEGG D09889
Routes of administration Subcutaneous


Trulicity is given as a subcutaneous (under skin) injection that is administered 1 time per week.

Injection may be administered in abdomen (excluding 2” radius around navel), things, or back of upper arms. Do not use the same location for repeated injections to avoid the chance of developing lipodystrophy. Inject in a new one of the three potential locations each time, and most people will alternate between the 3.


Make sure Trulicity pen is locked.

Pull the base cap straight off and dispose.

Be sure to not put the Base Cap back on as this could damage the needle.

Place the Clear Base flat and firmly against your skin at the injection site.

Unlock by turning the lock ring.

Press and hold the green injection button to hear a loud click sound.

Continue holding the base of the pen firmly against your skin until you hear a second click and given yourself the injection while waiting to hear a second click which indicated the needle starts retracting in about 5-10 seconds.

Remove Trulicity pen from your skin.


The active ingredient in Trulicity is Dulaglutide.


Tell your doctor if you have any history of kidney disease, pancreatitis, stomach or intestinal disorders like gastroparesis, or eye problems like diabetic retinopathy before starting on Trulicity.

Medication may cause temporarily blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Driving or using machinery may be inadvisable until your vision stabilizes.

Limit alcohol consumption while taking this medication.


There is the possibility of negative drug interaction risks between Trulicity and other Rx medications, including:

  • Amlodipine
  • Atorvastatin
  • Furosemide
  • Gabapentin
  • Glimepiride
  • Glipizide
  • Hydrochlorothiazide
  • Empagliflozin
  • Levothyroxine
  • Lisinopril
  • Losartan
  • Metformin
  • Metoprolol
  • Omeprazole
  • Pantoprazole
  • Rosuvastatin
  • Trazodone

It is always best to advise your doctor of all medications you are currently taking before receiving a prescription and proceeding to buy Trulicity.

Side Effects

Trulicity side effects are possible, and some users may experience nausea, diarrhea, vomiting, abdominal pain, decrease appetite, tiredness, or weakness. If Trulicity side effects are seen you may want to discontinue medication use and speak with your doctor again regarding diabetes pen alternatives.

Frequently Asked Questions about Trulicity

What is Trulicity?

Trulicity is a prescription medication that comes in a pre-filled pen. It is injected once a week under the skin, usually in the abdomen, thigh, or upper arm.

How does Trulicity work?

Trulicity works by mimicking the effects of a natural hormone called GLP-1. GLP-1 helps the body produce insulin, especially after meals, and it also slows down the stomach from emptying. This helps to lower blood sugar levels.

Who should take Trulicity?

Trulicity is approved for adults with type 2 diabetes. It is often used in combination with other diabetes medications, such as metformin, insulin, or sulfonylureas.

What are the side effects of Trulicity?

The most common side effects of Trulicity are nausea, vomiting, diarrhea, constipation, stomach pain, and injection site reactions. These side effects are usually mild and go away on their own within a few days or weeks.

How much does Trulicity cost?

The cost of Trulicity can vary depending on your insurance coverage. The average retail price is about $800 per month. However, there may be copay assistance programs available to help you afford the medication.

Can I take Trulicity if I am pregnant or breastfeeding?

Trulicity is not recommended for use during pregnancy or breastfeeding.

Can I drink alcohol while taking Trulicity?

There is no interaction between Trulicity and alcohol. However, it is important to drink alcohol in moderation if you have diabetes.

How can I lose weight while taking Trulicity?

Trulicity may help you lose weight, but it is not a weight loss medication. If you are looking to lose weight, talk to your doctor about a healthy diet and exercise plan.

Can I take Trulicity if I have kidney or liver disease?

Trulicity should be used with caution if you have kidney or liver disease. Talk to your doctor about whether Trulicity is right for you.

How can I dispose of used Trulicity pens?

Do not dispose of used Trulicity pens in the trash. Ask your pharmacist how to properly dispose of them.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

Product Code : 13886

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