Januvia (Sitagliptin Phosphate)

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Product Details


Januvia is a medicine for Type 2 diabetes. It helps manage blood sugar when you follow a special diet and exercise more. Its main ingredient, Sitagliptin, belongs to a group called DPP-4 inhibitors. It boosts insulin and lowers glucagon, a hormone that increases blood sugar. This happens by affecting certain hormones that an enzyme, dipeptidyl peptidase 4, usually breaks down.

In the 100mg dose, Januvia has shown good results in three diabetes tests:

  • hemoglobin A1C (which shows long-term blood sugar control)
  • fasting blood sugar, and
  • blood sugar after eating

Always talk with your doctor about how well it works and its possible side effects before you buy Januvia .

Fact Table
Formula C16H15F6N5O
License US FDA, EU EMA
Bioavailability 87%
Legal status Rx-Only
Chemical Name Sitagliptin Phosphate
Elimination half-life 8-14 hours
Dosage (Strength) 25mg, 50mg, 100mg
Pregnancy Consult a doctor
Brands Januvia
Protein binding 38%
PubChem CID 4369359
MedlinePlus a606023
ChEBI 40237
ATC code A10BH01
DrugBank DB01261
KEGG D08516
Routes of administration By mouth (tablets)


Standard dosage is Januvia 100mg taken once daily, with or without food. Dosage may vary based on doctor’s assessment of patient condition and any responses to existing treatment. Always take medication exactly as shown in your prescription.


The active ingredient in Januvia is Sitagliptin.


Tell your doctor if you have any history of:

  • kidney disease
  • heart disease
  • gallstones
  • high blood triglyceride levels
  • pancreatitis
  • or history of excessive alcohol use before starting on Januvia

For use with ages 18 and up.

Januvia is not to be used by people with Type 1 diabetes.

Medication is not effective for the treatment of type 1 diabetes or for diabetic ketoacidosis.

Be aware of expiry date for the medication.


There is the possibility of negative drug interactions risks between Januvia and other RX or OTC medications, including

  • Amlodipine
  • Aspirin
  • Atorvastatin (Lipitor)
  • Carvedilol
  • Furosemide
  • Gabapentin
  • Glimepiride
  • Glipizide
  • Hydrochlorothiazide
  • Levothyroxine
  • Lisinopril
  • Losartan
  • Metformin
  • Metoprolol
  • Omeprazole
  • Pantoprazole
  • Simvastatin

Tell your doctor of all medications you are currently taking before receiving a prescription and proceeding to buy Januvia online.

Side Effects

Januvia side effects are possible, and some users may experience:

  • nasopharyngitis
  • upper respiratory tract infections
  • diarrhea
  • headache

If side effects from Januvia are experienced you may want to discontinue use and speak to your doctor.

Frequently Asked Questions about Januvia

What is Januvia and what is it used for?

Januvia is a prescription medication used to control blood sugar levels in adults with type 2 diabetes. It belongs to a class of drugs called incretin mimetics, which work by helping your body release more insulin after you eat.

What are the side effects of Januvia?

The most common side effects of Januvia are mild and include nausea, diarrhea, headache, and upper respiratory tract infections. More serious side effects are rare but can include pancreatitis, allergic reactions, and kidney problems.

How do I take Januvia?

Januvia is typically taken once a day with or without food. It is important to take it exactly as prescribed by your doctor and not to skip doses.

Does Januvia cause weight gain or loss?

Januvia is not known to cause significant weight gain or loss. However, some people may experience weight loss as a result of better blood sugar control.

Can I take Januvia if I have other medical conditions?

It is important to tell your doctor about all of your medical conditions before taking Januvia, including kidney or liver problems, heart failure, and a history of pancreatitis. Januvia may not be right for everyone.

Can I take Januvia with other medications?

Tell your doctor about all the medications you are taking, including over-the-counter medications and herbal supplements, before starting Januvia. Some medications can interact with Januvia and increase your risk of side effects.

How long does it take for Januvia to work?

Januvia can start to lower your blood sugar levels within a few weeks, but it may take several months to reach its full effect.

What should I do if I miss a dose of Januvia?

If you miss a dose of Januvia, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

What should I eat or drink while taking Januvia?

Januvia can be taken with or without food. However, it is important to eat a healthy diet and exercise regularly to control your blood sugar levels.

What should I do if I have questions about Januvia?

Talk to your doctor or pharmacist if you have any questions about Januvia. They can provide you with more information about the medication and how to take it safely and effectively.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your healthcare professional for medical advice and treatment.

Product Code : 13883

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