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Steglujan is a medicine for Type 2 diabetes. It helps control blood sugar in people who are insulin resistant. It has two main ingredients that do two things: help your body make more insulin and make less sugar. It also helps move more sugar into cells for energy. Better diet and more cardiovascular exercise can improve its effectiveness.
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| Fact Table | |
|---|---|
| Formula | C22H25ClO7, C16H15F6N5O |
| License | US DailyMed, US FDA, EU EMA |
| Bioavailability | ~100%, 87% |
| Legal status | Rx-Only |
| Chemical Name | Ertugliflozin / Sitagliptin |
| Elimination half-life | ~17 hours, 8 to 14 h |
| Dosage (Strength) | 5mg/100mg, 15mg/100mg |
| Pregnancy | Consult with healthcare provider |
| Brands | Steglujan |
| Protein binding | 93.6%, 38% |
| PubChem CID | 44814423, 4369359 |
| MedlinePlus | a606023 |
| ChEBI | 40237 |
| ATC code | A10BK04, A10BH01 |
| DrugBank | DB11827, DB01261 |
| KEGG | D10313, D08516 |
| Routes of administration | By mouth |
Dosage strength will be 5mg / 100mg or 15mg / 100 tablets taken once daily in the morning, with or without food.
The active ingredients in Steglujan are Ertuglflozin / Sitagliptin.
Let your doctor know of any history of:
Medication may cause drowsiness, dizziness, or blurred vision.
Limit alcohol consumption when using this medication.
Older adults may be more susceptible to Steglujan side effects.
Keep medication in a cool, dry place and be aware of expiry date.
Negative drug interactions may occur between Steglujan and the following Rx medications:
Steglujan side effects can occur, and some users may have:
If side effects are seen, you may want to stop use and talk to your doctor.
What is Steglujan?
Steglujan is a combination of ertugliflozin and sitagliptin used to improve blood sugar control in adults with type 2 diabetes mellitus, in conjunction with diet and exercise. It is not for treating type 1 diabetes.
Who should not use Steglujan?
Avoid Steglujan if you have severe kidney disease, are on dialysis, have diabetic ketoacidosis, or are allergic to ertugliflozin or sitagliptin.
What should I tell my doctor before taking Steglujan?
Inform your doctor if you have a history of diabetic ketoacidosis, liver or kidney disease, bladder infections, pancreatitis, diabetic foot ulcers, heart problems, gallstones, high triglycerides, or if you are pregnant or breastfeeding.
How should I take Steglujan?
Take Steglujan once per day in the morning, with or without food. Follow your doctor's instructions and prescription label carefully.
What is the usual dosage for Steglujan?
The initial dose is typically one tablet (ertugliflozin 5 mg/sitagliptin 100 mg) per day. Depending on your response and need for additional glycemic control, it may be increased to ertugliflozin 15 mg/sitagliptin 100 mg per day.
What should I do if I miss a dose or overdose?
If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose. In case of overdose, seek emergency medical attention.
Are there any substances to avoid while taking Steglujan?
Avoid alcohol and getting up too fast from a sitting or lying position to prevent dizziness.
How does Steglujan interact with other drugs?
Steglujan can interact with other medications, including over-the-counter medicines, vitamins, and herbal products. Always inform your doctor about all medications you are taking.
